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Chimaerin Suppresses Rac1 Activation at the Apical Membrane to Maintain the Cyst Structure
Epithelial organs are made of a well-polarized monolayer of epithelial cells, and their morphology is maintained strictly for their proper functions. Previously, we showed that Rac1 activation is suppressed at the apical membrane in the mature organoid, and that such spatially biased Rac1 activity i...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527519/ https://ncbi.nlm.nih.gov/pubmed/23284959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052258 |
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