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Chimaerin Suppresses Rac1 Activation at the Apical Membrane to Maintain the Cyst Structure

Epithelial organs are made of a well-polarized monolayer of epithelial cells, and their morphology is maintained strictly for their proper functions. Previously, we showed that Rac1 activation is suppressed at the apical membrane in the mature organoid, and that such spatially biased Rac1 activity i...

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Detalhes bibliográficos
Main Authors: Yagi, Shunsuke, Matsuda, Michiyuki, Kiyokawa, Etsuko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527519/
https://ncbi.nlm.nih.gov/pubmed/23284959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052258
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