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Suppression of Rac1 activity at the apical membrane of MDCK cells is essential for cyst structure maintenance
Using MDCK cells that constitutively express a Förster resonance energy transfer biosensor, we found that Rac1 activity is homogenous at the entire plasma membrane in early stages of cystogenesis, whereas in later stages Rac1 activity is higher at the lateral membrane than at the apical plasma membr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323125/ https://ncbi.nlm.nih.gov/pubmed/22261715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.249 |
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