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The Adjuvant Double Mutant Escherichia coli Heat Labile Toxin Enhances IL-17A Production in Human T Cells Specific for Bacterial Vaccine Antigens

The strong adjuvant activity and low enterotoxicity of the novel mucosal adjuvant double mutant Escherichia coli heat labile toxin, LT(R192G/L211A) or dmLT, demonstrated in mice, makes this molecule a promising adjuvant candidate. However, little is known about the mechanisms responsible for the adj...

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Detalhes bibliográficos
Main Authors: Leach, Susannah, Clements, John D., Kaim, Joanna, Lundgren, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527457/
https://ncbi.nlm.nih.gov/pubmed/23284753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051718
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