Cellular Redox Imbalance and Changes of Protein S-glutathionylation Patterns Are Associated with Senescence Induced by Oncogenic H-Ras

H-Ras oncogene requires deregulation of additional oncogenes or inactivation of tumor suppressor proteins to increase cell proliferation rate and transform cells. In fact, the expression of the constitutively activated H-RasV12 induces cell growth arrest and premature senescence, which act like barr...

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Detalhes bibliográficos
Main Authors: Armeni, Tatiana, Ercolani, Luisa, Urbanelli, Lorena, Magini, Alessandro, Magherini, Francesca, Pugnaloni, Armanda, Piva, Francesco, Modesti, Alessandra, Emiliani, Carla, Principato, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527427/
https://ncbi.nlm.nih.gov/pubmed/23284910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052151
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