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Phosphonopeptides as Antibacterial Agents: Mechanism of Action of Alaphosphin

The novel antibacterial peptide mimetic alaphosphin (l-alanyl-l-1-aminoethylphosphonic acid) selectively inhibited peptidoglycan biosynthesis in both gram-negative and gram-positive bacteria. It induced accumulation of uridine diphosphate-N-acetyl-muramyl-tripeptide in gram-positive organisms and si...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Atherton, Frank R., Hall, Michael J., Hassall, Cedric H., Lambert, Robert W., Lloyd, William J., Ringrose, Peter S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1979
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/525987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.696
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