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The Guanine Nucleotide Exchange Factor Kalirin-7 Is a Novel Synphilin-1 Interacting Protein and Modifies Synphilin-1 Aggregate Transport and Formation

Synphilin-1 has been identified as an interaction partner of α-synuclein, a key protein in the pathogenesis of Parkinson disease (PD). To further explore novel binding partners of synphilin-1, a yeast two hybrid screening was performed and kalirin-7 was identified as a novel interactor. We then inve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tsai, Yu-Chun, Riess, Olaf, Soehn, Anne S., Nguyen, Huu Phuc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527391/
https://ncbi.nlm.nih.gov/pubmed/23284848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051999
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