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Modeling coding-sequence evolution within the context of residue solvent accessibility
BACKGROUND: Protein structure mediates site-specific patterns of sequence divergence. In particular, residues in the core of a protein (solvent-inaccessible residues) tend to be more evolutionarily conserved than residues on the surface (solvent-accessible residues). RESULTS: Here, we present a mode...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527230/ https://ncbi.nlm.nih.gov/pubmed/22967129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-179 |
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