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Effect of Acycloguanosine Treatment on Acute and Latent Herpes Simplex Infections in Mice
Systemic treatment of mice with the nucleoside analog 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine [aciclovir]) was found to be highly effective against acute type 1 herpes simplex virus infection of the pinna. The drug ablated clinical signs and reduced virus replication both in tissue local t...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1979
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352710/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/464587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.4.554 |
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