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Effect of Acycloguanosine Treatment on Acute and Latent Herpes Simplex Infections in Mice

Systemic treatment of mice with the nucleoside analog 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine [aciclovir]) was found to be highly effective against acute type 1 herpes simplex virus infection of the pinna. The drug ablated clinical signs and reduced virus replication both in tissue local t...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Field, Hugh J., Bell, Susanne E., Elion, Gertrude B., Nash, Anthony A., Wildy, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1979
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/464587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.4.554
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