Inactivation of SNF5 Cooperates with p53 Loss to Accelerate Tumor Formation in Snf5(+/-);p53(+/-) Mice

Malignant rhabdoid tumors (MRTs) are poorly differentiated pediatric cancers that arise in various anatomical locations and have a very poor outcome. The large majority of these malignancies are caused by loss of function of the SNF5/INI1 component of the SWI/SNF chromatin remodeling complex. Howeve...

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Detalhes bibliográficos
Main Authors: DelBove, Jessica, Kuwahara, Yasumichi, Mora-Blanco, E. Lorena, Godfrey, Virginia, Funkhouser, William K., Fletcher, Christopher D. M., Van Dyke, Terry, Roberts, Charles W. M., Weissman, Bernard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527082/
https://ncbi.nlm.nih.gov/pubmed/19676100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20568
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