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Chemical chaperones assist intracellular folding to buffer mutational variations

Hidden genetic variations harbor potential for the evolution of new traits. Molecular chaperones, that assist protein folding, may conceal genetic variations in protein coding regions. Here, we investigate if the chemical milieu of cells has the potential to alleviate intracellular protein folding;...

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Detalhes bibliográficos
Main Authors: Bandyopadhyay, Anannya, Saxena, Kanika, Kasturia, Neha, Dalal, Vijit, Bhatt, Niraj, Rajkumar, Asher, Maity, Shuvadeep, Sengupta, Shantanu, Chakraborty, Kausik
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527004/
https://ncbi.nlm.nih.gov/pubmed/22246401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.768
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