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Chemical chaperones assist intracellular folding to buffer mutational variations

Hidden genetic variations harbor potential for the evolution of new traits. Molecular chaperones, that assist protein folding, may conceal genetic variations in protein coding regions. Here, we investigate if the chemical milieu of cells has the potential to alleviate intracellular protein folding;...

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Hlavní autoři: Bandyopadhyay, Anannya, Saxena, Kanika, Kasturia, Neha, Dalal, Vijit, Bhatt, Niraj, Rajkumar, Asher, Maity, Shuvadeep, Sengupta, Shantanu, Chakraborty, Kausik
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527004/
https://ncbi.nlm.nih.gov/pubmed/22246401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.768
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