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Influence of temperature on formation of perfect tau fragment fibrils using PRIME20/DMD simulations

We investigate the fibrillization process for amyloid tau fragment peptides (VQIVYK) by applying the discontinuous molecular dynamics method to a system of 48 VQIVYK peptides modeled using a new protein model/force field, PRIME20. The aim of the article is to ascertain which factors are most importa...

詳細記述

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書誌詳細
主要な著者: Cheon, Mookyung, Chang, Iksoo, Hall, Carol K
フォーマット: Artigo
言語:Inglês
出版事項: Wiley Subscription Services, Inc., A Wiley Company 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526993/
https://ncbi.nlm.nih.gov/pubmed/22887126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2141
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