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Influence of temperature on formation of perfect tau fragment fibrils using PRIME20/DMD simulations
We investigate the fibrillization process for amyloid tau fragment peptides (VQIVYK) by applying the discontinuous molecular dynamics method to a system of 48 VQIVYK peptides modeled using a new protein model/force field, PRIME20. The aim of the article is to ascertain which factors are most importa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526993/ https://ncbi.nlm.nih.gov/pubmed/22887126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2141 |
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