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The SirT3 Divining Rod Points to Oxidative Stress
Sirtuins are NAD-dependent deacetylases that counter aging and diseases of aging. Sirtuin research has focused on SirT1, which deacetylates transcription factors and cofactors in the nucleus. More recent findings highlight SirT3 as a mitochondrial sirtuin that regulates metabolism and oxidative stre...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526939/ https://ncbi.nlm.nih.gov/pubmed/21658599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.008 |
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