Llwytho...

A colitis locus on chromosome 2 impacting the severity of early-onset disease in mice deficient in GPX1 and GPX2

BACKGROUND: Genetic background has a profound effect on inflammatory bowel disease. The Gpx1 and Gpx2 double knockout (GPX1/2-DKO) mice on a mixed C57BL/6 (B6) and 129S1/SvimJ (129) background had spontaneous ileocolitis. The DKO mice on a B6 background had mild ileocolitis. We characterized the 129...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Esworthy, R. Steven, Kim, Byung-Wook, Larson, Garrett P., Yip, M.L. Richard, Smith, David D., Li, Min, Chu, Fong-Fong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526817/
https://ncbi.nlm.nih.gov/pubmed/20872835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21479
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!