Llwytho...

Phylogenetic conservation of the 3′ cryptic recombination signal sequence (3′cRSS) in the VH genes of jawed vertebrates

The VH replacement process is a RAG-mediated secondary recombination in which the variable region of a rearranged VHDJH is replaced by a different germline VH gene. In almost all human and mouse VH genes, two sequence features appear to be crucial for VH replacement. First, an embedded heptamer, whi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sun, Yi, Liu, Zhancai, Li, Zhaoyong, Lian, Zhengxing, Zhao, Yaofeng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526766/
https://ncbi.nlm.nih.gov/pubmed/23267360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00392
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