טוען...
Phylogenetic conservation of the 3′ cryptic recombination signal sequence (3′cRSS) in the VH genes of jawed vertebrates
The VH replacement process is a RAG-mediated secondary recombination in which the variable region of a rearranged VHDJH is replaced by a different germline VH gene. In almost all human and mouse VH genes, two sequence features appear to be crucial for VH replacement. First, an embedded heptamer, whi...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526766/ https://ncbi.nlm.nih.gov/pubmed/23267360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00392 |
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