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Pseudouridine Monophosphate Glycosidase: a New Glycosidase Mechanism(,)

Pseudouridine (Ψ), the most abundant modification in RNA, is synthesized in situ using Ψ synthase. Recently, a pathway for the degradation of Ψ was described. In this pathway Ψ is first converted to Ψ 5′-monophosphate (ΨMP) by Ψ kinase and then ΨMP is degraded by ΨMP glycosidase to uracil and ribose...

詳細記述

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書誌詳細
主要な著者: Huang, Siyu, Mahanta, Nilkamal, Begley, Tadhg P., Ealick, Steven E.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526674/
https://ncbi.nlm.nih.gov/pubmed/23066817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3006829
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