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Inactivation of MARCH5 Prevents Mitochondrial Fragmentation and Interferes with Cell Death in a Neuronal Cell Model
PURPOSE: To study the impact of the mitochondrial ubiquitin ligase MARCH5 on mitochondrial morphology and induction of apoptosis using an in vitro model of neuronal precursor cells exposed to glaucoma-relevant stress conditions. METHODS: RGC5 cells transfected with expression constructs for MARCH5,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526576/ https://ncbi.nlm.nih.gov/pubmed/23285122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052637 |
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