The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia

BACKGROUND: The protein alpha-synuclein (α-SYN), which is found in the Lewy bodies of dopamine-producing (DA) neurons in the substantia nigra (SN), has an important role in the pathogenesis of Parkinson’s disease (PD). Previous studies have shown that neuroinflammation plays a key role in PD pathoge...

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Hlavní autoři: Cao, Shuwen, Standaert, David G, Harms, Ashley S
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526448/
https://ncbi.nlm.nih.gov/pubmed/23186369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-259
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