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Reconstructing genome mixtures from partial adjacencies

Many cancer genome sequencing efforts are underway with the goal of identifying the somatic mutations that drive cancer progression. A major difficulty in these studies is that tumors are typically heterogeneous, with individual cells in a tumor having different complements of somatic mutations. How...

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Autori principali: Mahmoody, Ahmad, Kahn, Crystal L, Raphael, Benjamin J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526445/
https://ncbi.nlm.nih.gov/pubmed/23282028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S19-S9
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