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BCL6 positively regulates AID and germinal center gene expression via repression of miR-155

The BCL6 proto-oncogene encodes a transcriptional repressor that is required for germinal center (GC) formation and whose de-regulation is involved in lymphomagenesis. Although substantial evidence indicates that BCL6 exerts its function by repressing the transcription of hundreds of protein-coding...

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Detalhes bibliográficos
Main Authors: Basso, Katia, Schneider, Christof, Shen, Qiong, Holmes, Antony B., Setty, Manu, Leslie, Christina, Dalla-Favera, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526356/
https://ncbi.nlm.nih.gov/pubmed/23166356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121387
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