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Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4
Ingestion of wheat, barley, or rye triggers small intestinal inflammation in patients with celiac disease. Specifically, the storage proteins of these cereals (gluten) elicit an adaptive Th1-mediated immune response in individuals carrying HLA-DQ2 or HLA-DQ8 as major genetic predisposition. This wel...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526354/ https://ncbi.nlm.nih.gov/pubmed/23209313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102660 |
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