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Development of Novel Recombinant AAV Vectors and Strategies for the Potential Gene Therapy of Hemophilia

Recombinant vectors based on a non-pathogenic human parvovirus, the adeno-associated virus (AAV), have gained attention as a potentially safe and useful alternative to the more commonly used retroviral and adenoviral vectors. AAV vectors are currently in use in Phase I/II clinical trials for gene th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhong, Li, Jayandharan, Giridhara R., Aslanidi, George V., Zolotukhin, Sergei, Herzog, Roland W., Srivastava, Arun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526190/
https://ncbi.nlm.nih.gov/pubmed/23264889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7412.S1-008
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