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A sequence-based approach demonstrates that balancing selection in classical human leukocyte antigen (HLA) loci is asymmetric
Balancing selection has maintained human leukocyte antigen (HLA) allele diversity, but it is unclear whether this selection is symmetric (all heterozygotes are comparable and all homozygotes are comparable in terms of fitness) or asymmetric (distinct heterozygote genotypes display greater fitness th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526157/ https://ncbi.nlm.nih.gov/pubmed/23065702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds424 |
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