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Analysis of maternal–offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes

AIM: Type 1 diabetes (T1D) is a complex trait for which variation in the classical human leucocyte antigen (HLA) loci within the Major Histocompatibility Complex (MHC) significantly influences disease risk. To date, HLA class II DR-DQ genes confer the strongest known genetic effect in T1D. HLA loci...

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Main Authors: Bronson, P. G., Ramsay, P. P., Thomson, G., Barcellos, L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635943/
https://ncbi.nlm.nih.gov/pubmed/19143818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2008.01006.x
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