Analysis of Maternal–Offspring HLA Compatibility, Parent-of-Origin Effects, and Noninherited Maternal Antigen Effects for HLA–DRB1 in Systemic Lupus Erythematosus

OBJECTIVE: Genetic susceptibility to systemic lupus erythematosus (SLE) is well established, with the HLA class II DRB1 and DQB1 loci demonstrating the strongest association. However, HLA may also influence SLE through novel biologic mechanisms in addition to genetic transmission of risk alleles. Ev...

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Detalhes bibliográficos
Main Authors: Bronson, Paola G., Komorowski, Leanne K., Ramsay, Patricia P., May, Suzanne L., Noble, Janelle, Lane, Julie A., Thomson, Glenys, Claas, Frans H., Seldin, Michael F., Kelly, Jennifer A., Harley, John B., Moser, Kathy L., Gaffney, Patrick M., Behrens, Timothy, Criswell, Lindsey A., Barcellos, Lisa F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948464/
https://ncbi.nlm.nih.gov/pubmed/20191587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27426
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