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Analysis of Maternal–Offspring HLA Compatibility, Parent-of-Origin Effects, and Noninherited Maternal Antigen Effects for HLA–DRB1 in Systemic Lupus Erythematosus

OBJECTIVE: Genetic susceptibility to systemic lupus erythematosus (SLE) is well established, with the HLA class II DRB1 and DQB1 loci demonstrating the strongest association. However, HLA may also influence SLE through novel biologic mechanisms in addition to genetic transmission of risk alleles. Ev...

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Bibliografski detalji
Glavni autori: Bronson, Paola G., Komorowski, Leanne K., Ramsay, Patricia P., May, Suzanne L., Noble, Janelle, Lane, Julie A., Thomson, Glenys, Claas, Frans H., Seldin, Michael F., Kelly, Jennifer A., Harley, John B., Moser, Kathy L., Gaffney, Patrick M., Behrens, Timothy, Criswell, Lindsey A., Barcellos, Lisa F.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948464/
https://ncbi.nlm.nih.gov/pubmed/20191587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27426
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