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Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leap

Despite its wide existence, the adaptive role of aneuploidy (the abnormal state of having unequal number of different chromosomes) has been a subject of debate. Cellular aneuploidy has been associated with enhanced resistance to stress, whereas on the organismal level it is detrimental to multi-cell...

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Detalhes bibliográficos
Main Authors: Chen, Guangbo, Rubinstein, Boris, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526072/
https://ncbi.nlm.nih.gov/pubmed/22926916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200069
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