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Hsp90 Stress Potentiates Rapid Cellular Adaptation through Induction of Aneuploidy
Aneuploidy, a state of having uneven numbers of chromosomes, is a form of large-effect mutation able to confer adaptive phenotypes under diverse stress conditions(1,2). Here we investigate whether pleiotropic stress could in turn induce aneuploidy in budding yeast. We show that while diverse stresse...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276732/ https://ncbi.nlm.nih.gov/pubmed/22286062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10795 |
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