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A prescription for ‘stress’ - the role of Hsp90 in genome stability and cellular adaptation

Changes in cell homeostasis, or cell ‘stress’, are thought to tax the ability of the Hsp90 chaperone to facilitate an array of processes critical for genome maintenance. Here, we review the current understanding of how Hsp90 chaperone machinery ensures the function of proteins important for DNA repa...

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Detalles Bibliográficos
Main Authors: Kaplan, Kenneth B., Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479336/
https://ncbi.nlm.nih.gov/pubmed/22959309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.08.006
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