The DNA damage- and transcription- associated protein Paxip1 controls thymocyte development and emigration

Histone 3 lysine 4 trimethylation (H3K4me3) is associated with promoters of active genes and found at hot spots for DNA recombination. Here we have shown that PAXIP1, a protein associated with MLL3 and MLL4 methyltransferase and the DNA damage response, regulates RAG-mediated cleavage and repair dur...

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Библиографические подробности
Главные авторы: Callen, Elsa, Faryabi, Robert B., Luckey, Megan, Hao, Bingtao, Daniel, Jeremy A., Yang, Wenjing, Sun, Hong-Wei, Dressler, Greg, Peng, Weiqun, Chi, Hongbo, Ge, Kai, Krangel, Michael S., Park, Jung-Hyun, Nussenzweig, André
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525809/
https://ncbi.nlm.nih.gov/pubmed/23159437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.10.007
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