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Signal integration and cross-talk during thymocyte migration and emigration
The thymus produces self-tolerant functionally competent T cells. This occurs by the import of multipotent hematopoietic progenitors that are signalled to adopt the T cell fate. Expression of T cell specific genes, including those encoding the T cell receptor (TCR), is followed by positive and negat...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710714/ https://ncbi.nlm.nih.gov/pubmed/21701522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2989 |
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