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A Rhodamine-Labeled Citalopram Analogue as a High-Affinity Fluorescent Probe for the Serotonin Transporter

A novel fluorescent ligand was synthesized as a high-affinity, high specificity probe for visualizing the serotonin transporter (SERT). The rhodamine fluorophore was extended from an aniline substitution on the 5- position of the dihydroisobenzofuran ring of citalopram (2, 1-(3-(dimethylamino)propyl...

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Bibliographic Details
Main Authors: Zhang, Peng, Jørgensen, Trine Nygaard, Loland, Claus J., Newman, Amy Hauck
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525792/
https://ncbi.nlm.nih.gov/pubmed/23168018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.10.089
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