p38 MAPK in myeloma cells regulates osteoclast and osteoblast activity and induces bone destruction

p38 MAPK which is constitutively activated in human myeloma has been implicated in bone destruction by this cancer, but the processes it recruits are obscure. In this study, we demonstrate that p38 activity in myeloma inhibits osteoblast differentiation and bone formation but also enhances osteoclas...

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Autors principals: He, Jin, Liu, Zhiqiang, Zheng, Yuhuan, Qian, Jianfei, Li, Haiyan, Lu, Yong, Xu, Jingda, Hong, Bangxing, Zhang, Mingjun, Lin, Pei, Cai, Zhen, Orlowski, Robert Z., Kwak, Larry W., Yi, Qing, Yang, Jing
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525770/
https://ncbi.nlm.nih.gov/pubmed/23066034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2664
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