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Modulation of the ATPase and transport activities of broad-acting multidrug resistance factor ABCC10 (MRP7)
The cell surface molecule ABCC10 is a broad-acting transporter of xenobiotics, including cancer drugs such as taxanes, epothilone B, and modulators of the estrogen pathway. Abcc10(−/−) mice exhibit increased tissue sensitivity and lethality resulting from paclitaxel exposure compared to wild-type co...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525726/ https://ncbi.nlm.nih.gov/pubmed/23087055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1340 |
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