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Contribution of Abcc10 (Mrp7) to in vivo paclitaxel resistance as assessed in Abcc10(−/−) mice

Recently we reported that the ATP-binding cassette transporter Abcc10, also known as multidrug resistance protein 7 (Mrp7), is able to confer resistance to a variety of anticancer agents including taxanes. However, the in vivo functions of the pump have not been determined to any extent. Here we gen...

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Autors principals: Hopper-Borge, Elizabeth A., Churchill, Timothy, Paulose, Chelsy, Nicolas, Emmanuelle, Jacobs, Joely D., Ngo, Olivia, Kuang, Yehong, Grinberg, Alex, Westphal, Heiner, Chen, Zhe-Sheng, Klein-Szanto, Andres J., Belinsky, Martin G., Kruh, Gary D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096848/
https://ncbi.nlm.nih.gov/pubmed/21576088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3623
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