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Targeting MDSCs enhance therapeutic vaccination responses against lung cancer
Myeloid-derived suppressor cells (MDSCs) are important regulators of immune responses. These cells suppress the cytotoxic activities of natural killer (NK)-cell and T-cell effectors and promote tumor growth. We demonstrated that depleting MDSCs improve therapeutic responses to vaccination in a murin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525634/ https://ncbi.nlm.nih.gov/pubmed/23264925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21970 |
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