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Targeting MDSCs enhance therapeutic vaccination responses against lung cancer

Myeloid-derived suppressor cells (MDSCs) are important regulators of immune responses. These cells suppress the cytotoxic activities of natural killer (NK)-cell and T-cell effectors and promote tumor growth. We demonstrated that depleting MDSCs improve therapeutic responses to vaccination in a murin...

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Détails bibliographiques
Auteurs principaux: Srivastava, Minu K., Dubinett, Steven, Sharma, Sherven
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525634/
https://ncbi.nlm.nih.gov/pubmed/23264925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21970
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