Chemoimmunotherapy for advanced gastrointestinal carcinomas: A successful combination of gene therapy and cyclophosphamide

The combination of a single low dose of cyclophosphamide (Cy) with the adenovirus-mediated gene transfer of interleukin-12 (AdIL-12) might represent a successful therapy for experimental gastrointestinal tumors. This approach has been proven to revert immunosuppressive mechanisms elicited by cancer...

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Autores principales: Malvicini, Mariana, Piccioni, Flavia, Bayo, Juan, Fiore, Esteban, Atorrasagasti, Catalina, Alaniz, Laura, Garcia, Mariana, Aquino, Jorge B., Gidekel, Manuel, Matar, Pablo, Mazzolini, Guillermo
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525625/
https://ncbi.nlm.nih.gov/pubmed/23264916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21651
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