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Next-generation sequencing identified new oncogenes and tumor suppressor genes in human hepatic tumors
Genetic studies were performed in a French series of hepatocellular carcinomas. New oncogenes (NFE2L2) and tumor suppressor genes (IRF2, ARID1A and RPS6K3) were found to be recurrently altered. Moreover, a genotoxic signature was identified, raising the possible implication of a genotoxic exposure i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525620/ https://ncbi.nlm.nih.gov/pubmed/23264911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21480 |
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