Sequence Variants of Toll Like Receptor 4 and Late-Onset Alzheimer's Disease

BACKGROUND: Toll like receptor 4 (TLR4) has been related to inflammation and beta-amyloid deposition in Alzheimer's disease (AD) brain. No study has explored the association between haplotype-tagging single nucleotide polymorphisms (htSNPs) of TLR4 and AD risk previously and ApoE e4 status alon...

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Main Authors: Chen, Yen-Ching, Yip, Ping-Keung, Huang, Yi-Ling, Sun, Yu, Wen, Li-Li, Chu, Yi-Min, Chen, Ta-Fu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525588/
https://ncbi.nlm.nih.gov/pubmed/23272070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050771
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