The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons

BACKGROUND: Compound 48/80 is widely used in animal and tissue models as a “selective” mast cell activator. With this study we demonstrate that compound 48/80 also directly activates enteric neurons and visceral afferents. METHODOLOGY/PRINCIPAL FINDINGS: We used in vivo recordings from extrinsic int...

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Autores principales: Schemann, Michael, Kugler, Eva Maria, Buhner, Sabine, Eastwood, Christopher, Donovan, Jemma, Jiang, Wen, Grundy, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525567/
https://ncbi.nlm.nih.gov/pubmed/23272218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052104
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