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Regulated in Development and DNA Damage Responses -1 (REDD1) Protein Contributes to Insulin Signaling Pathway in Adipocytes

REDD1 (Regulated in development and DNA damage response 1) is a hypoxia and stress response gene and is a negative regulator of mTORC1. Since mTORC1 is involved in the negative feedback loop of insulin signaling, we have studied the role of REDD1 on insulin signaling pathway and its regulation by in...

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Détails bibliographiques
Auteurs principaux: Regazzetti, Claire, Dumas, Karine, Le Marchand-Brustel, Yannick, Peraldi, Pascal, Tanti, Jean-François, Giorgetti-Peraldi, Sophie
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525563/
https://ncbi.nlm.nih.gov/pubmed/23272222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052154
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