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Hypoxia Decreases Insulin Signaling Pathways in Adipocytes

OBJECTIVE—Obesity is characterized by an overgrowth of adipose tissue that leads to the formation of hypoxic areas within this tissue. We investigated whether this phenomenon could be responsible for insulin resistance by studying the effect of hypoxia on the insulin signaling pathway in adipocytes....

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Detalhes bibliográficos
Main Authors: Regazzetti, Claire, Peraldi, Pascal, Grémeaux, Thierry, Najem-Lendom, Rosanna, Ben-Sahra, Issam, Cormont, Mireille, Bost, Frédéric, Le Marchand-Brustel, Yannick, Tanti, Jean-François, Giorgetti-Peraldi, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606898/
https://ncbi.nlm.nih.gov/pubmed/18984735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0457
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