Hypoxia Decreases Insulin Signaling Pathways in Adipocytes

OBJECTIVE—Obesity is characterized by an overgrowth of adipose tissue that leads to the formation of hypoxic areas within this tissue. We investigated whether this phenomenon could be responsible for insulin resistance by studying the effect of hypoxia on the insulin signaling pathway in adipocytes....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Regazzetti, Claire, Peraldi, Pascal, Grémeaux, Thierry, Najem-Lendom, Rosanna, Ben-Sahra, Issam, Cormont, Mireille, Bost, Frédéric, Le Marchand-Brustel, Yannick, Tanti, Jean-François, Giorgetti-Peraldi, Sophie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2009
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606898/
https://ncbi.nlm.nih.gov/pubmed/18984735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0457
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