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Insulin Induces REDD1 Expression through Hypoxia-inducible Factor 1 Activation in Adipocytes

REDD1 (regulated in development and DNA damage responses) is essential for the inhibition of mTORC1 (mammalian target of rapamycin complex) signaling pathway in response to hypoxia. REDD1 expression is regulated by many stresses such as hypoxia, oxidative stress, and energy depletion. However, the r...

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Bibliografiske detaljer
Main Authors: Regazzetti, Claire, Bost, Frédéric, Le Marchand-Brustel, Yannick, Tanti, Jean-François, Giorgetti-Peraldi, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820742/
https://ncbi.nlm.nih.gov/pubmed/19996311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047688
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