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Insulin Induces REDD1 Expression through Hypoxia-inducible Factor 1 Activation in Adipocytes

REDD1 (regulated in development and DNA damage responses) is essential for the inhibition of mTORC1 (mammalian target of rapamycin complex) signaling pathway in response to hypoxia. REDD1 expression is regulated by many stresses such as hypoxia, oxidative stress, and energy depletion. However, the r...

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Detalhes bibliográficos
Main Authors: Regazzetti, Claire, Bost, Frédéric, Le Marchand-Brustel, Yannick, Tanti, Jean-François, Giorgetti-Peraldi, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820742/
https://ncbi.nlm.nih.gov/pubmed/19996311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047688
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