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Insulin Induces REDD1 Expression through Hypoxia-inducible Factor 1 Activation in Adipocytes
REDD1 (regulated in development and DNA damage responses) is essential for the inhibition of mTORC1 (mammalian target of rapamycin complex) signaling pathway in response to hypoxia. REDD1 expression is regulated by many stresses such as hypoxia, oxidative stress, and energy depletion. However, the r...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820742/ https://ncbi.nlm.nih.gov/pubmed/19996311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047688 |
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