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Antibody Fragments Directed against Different Portions of the Human Neural Cell Adhesion Molecule L1 Act as Inhibitors or Activators of L1 Function

The neural cell adhesion molecule L1 plays important roles in neuronal migration and survival, neuritogenesis and synaptogenesis. L1 has also been found in tumors of different origins, with levels of L1 expression correlating positively with the metastatic potential of tumors. To select antibodies t...

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Autori principali: Wang, Yan, Loers, Gabriele, Pan, Hong-Chao, Gouveia, Ricardo, Zhao, Wei-Jiang, Shen, Yan-Qin, Kleene, Ralf, Costa, Julia, Schachner, Melitta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525558/
https://ncbi.nlm.nih.gov/pubmed/23272240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052404
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