Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Promotes Neuritogenesis and Cell Survival

The cell adhesion molecule L1 is a Lewis(x)-carrying glycoprotein that plays important roles in the developing and adult nervous system. Here we show that myelin basic protein (MBP) binds to L1 in a Lewis(x)-dependent manner. Furthermore, we demonstrate that MBP is released by murine cerebellar neur...

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Detalhes bibliográficos
Main Authors: Lutz, David, Loers, Gabriele, Kleene, Ralf, Oezen, Iris, Kataria, Hardeep, Katagihallimath, Nainesh, Braren, Ingke, Harauz, George, Schachner, Melitta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036357/
https://ncbi.nlm.nih.gov/pubmed/24671420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530238
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