Selective Protection of Human Liver Tissue in TNF-Targeting of Cancers of the Liver by Transient Depletion of Adenosine Triphosphate

BACKGROUND: Tumor necrosis factor alpha (TNF) is able to kill cancer cells via receptor-mediated cell death requiring adenosine triphosphate (ATP). Clinical usage of TNF so far is largely limited by its profound hepatotoxicity. Recently, it was found in the murine system that specific protection of...

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Detalhes bibliográficos
Main Authors: Weiland, Timo, Klein, Kathrin, Zimmermann, Martina, Speicher, Tobias, Venturelli, Sascha, Berger, Alexander, Bantel, Heike, Königsrainer, Alfred, Schenk, Martin, Weiss, Thomas S., Wendel, Albrecht, Schwab, Matthias, Bitzer, Michael, Lauer, Ulrich M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525543/
https://ncbi.nlm.nih.gov/pubmed/23272249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052496
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