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Selective Protection of Human Liver Tissue in TNF-Targeting of Cancers of the Liver by Transient Depletion of Adenosine Triphosphate

BACKGROUND: Tumor necrosis factor alpha (TNF) is able to kill cancer cells via receptor-mediated cell death requiring adenosine triphosphate (ATP). Clinical usage of TNF so far is largely limited by its profound hepatotoxicity. Recently, it was found in the murine system that specific protection of...

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Bibliografiske detaljer
Main Authors: Weiland, Timo, Klein, Kathrin, Zimmermann, Martina, Speicher, Tobias, Venturelli, Sascha, Berger, Alexander, Bantel, Heike, Königsrainer, Alfred, Schenk, Martin, Weiss, Thomas S., Wendel, Albrecht, Schwab, Matthias, Bitzer, Michael, Lauer, Ulrich M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525543/
https://ncbi.nlm.nih.gov/pubmed/23272249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052496
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